A field experiment was conducted during the two consecutive growing seasons (2010/2011 and 2011/2012) at Ezra’ Research Station/Deraa/Syria in order to evaluate the role of some agricultural practices in improving the performance of four wheat varieties (Acsad1105, Acsad1229, Acsad885 and Acsad901) under rainfed conditions. The experiment was laid according to factorial randomized complete block-split design with three replications. The mean average of early vigor, flag leaf area, peduncle length and leaf area index was significantly higher during the first growing season for the wheat variety (Acsad901) at the first planting date with a nitrogen amount of (150 kgN. Hectar1), and when nitrogen fertilizers were added twice (1.6-2.5, 53.4cm2, 16.3cm, 1.20 respectively). The mean average of the same studied aspects, however, was significantly lower during the second growing season in the case of the variety Acsad855 with regards to the early vigor, as well as in the case of the variety Acsad1129 in the case of the leaf area Flag at a late planting date, and without nitrogen fertilizers (3.6
4.5, 3.3 cm, 0.18, 16.6 cm2 respectively). The mean average of the grain yield was significantly higher during the first growing season for two wheat varieties (Acsad901, Acsad1229) at the first planting date, nitrogen rate 200 kgN. Ha-1, and when nitrogen fertilizers were added twice (660.4, 631.1 g.m-2 respectively), while it was significantly lower during the second growing season for the variety Acsad1105, at a late planting date, and without nitrogen fertilizers (127 g.m-2). Optimizing some important cultural practices helps increasing wheat grain yield by improving morpho-physiological traits related to yield particularly the size of source photo synthise (Leaf Area Index, Flag leaf area). The response of astivum wheat variety was better compared to durum wheat. This shows the importance of improving crop mangment factors in order to reach the maximum potential yield.